The aim of the retrospective study was to evaluate the effectiveness and toxicity of radiochemotherapy in patients with squamous cell carcinoma of the anal canal treated at a single institution. The treatment consisted of 3-dimensional conformal external beam radiotherapy with concurrent chemotherapy 5-fluorouracil and mytomycin Cfollowed by brachytherapy or external beam boost. The toxicity of therapy and its effectiveness were assessed.
Skip to Content. Use the menu to see other pages. Care for people diagnosed with cancer does not end when active treatment has finished.
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Skip to Content. Use the menu to see other pages. This section explains the types of treatments that are the standard of care for anal cancer. When making treatment plan decisions, you are encouraged to consider clinical trials as an option.
Once it's confirmed that you have anal cancer, your doctor may recommend additional tests to determine whether your cancer has spread to your lymph nodes or to other areas of your body. Your doctor uses the information from the procedures to assign your cancer a stage. The stages of anal cancer are indicated using Roman numerals ranging from 0 to IV, with the lowest stages indicating that the cancer is small and confined to the anus.
Although a rare disease, anal cancer is increasingly being diagnosed in patients with risk factors, mainly anal infection with the human papilloma virus. Magnetic resonance imaging MRI with external phased-array coils is recommended as the imaging modality of choice to grade anal cancers and to evaluate the response assessment after chemoradiotherapy, with a high contrast and good anatomic resolution of the anal canal. MRI provides a performant evaluation of size, extent and signal characteristics of the anal tumor before and after treatment, as well as lymph node involvement and extension to the adjacent organs.
Find information and resources for current and returning patients. Learn about clinical trials at MD Anderson and search our database for open studies. The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services.
The anus is an organ that lies at the end of the digestive tract below the rectum. It consists of two sections: the anal canal and the anus or anal verge. The anal canal is a cm long structure that lies between the anal sphincter one of the muscles that controls bowel movements just below the rectum and the anal verge which represents the transition point between the digestive tract and the skin on the outside of the body. Muscles within the anal canal and anus control the passage of stool from the rectum to outside the body.
Radiotherapy for anal cancer can cause side effects such as opening your bowels more often diarrhoea or making the skin around your anus sore. Everyone is different and the side effects vary from person to person. You may not have all of the effects mentioned.